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Pramod Murali, Ph.D. 2016

Electrical Engineering
Advisor: Prof. Boser
(510) 355-4643

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Research Interests: CMOS Sensors, Point of care diagnostics.
Job Interests: Internship in summer 2014 at an Industry R&D focused on point of care diagnostics

Pramod obtained his B.Tech degree in Electronics and Comm. Engg. from National Institute of Technology, Surathkal in 2009 and M.E degree in Microelectronic Systems from Indian Institute of Science, Bangalore in 2011. He worked as a Project Associate at the Centre for NanoScience and Engineering, Bangalore from 2011-2012. Currently he is a graduate student at U C Berkeley working with Prof. Bernhard Boser and Prof. Ali Niknejad.

Magnetic Particle Flow Cytometer [BPN649]
Flow Cytometry is a powerful technique used in health and disease diagnostics. This technique is used to
analyze and sort individual cells of a biological sample. Some of the applications include, HIV and cancer detection,
water quality monitoring, food safety among many others. Commercial equipments use laser source and an optical
detector to study cells labeled with fluorescent molecules. Such an approach is expensive, bulky and suffers from
optical background noise. We propose to replace the fluorescent markers with magnetic nano-particles (MNPs) to be
detected by CMOS chips. Apart from eliminating the need for sample preparation, this approach has the advantage of
being low cost, portable and disposable. Neelís relaxation of MNPs leads to a frequency dependent complex
susceptibility behaviour. The relaxation time constant depends on the nano-particle size and material. We use this
phenomenon to distinguish different cells. Currently, we are in the process of characterizing different MNPs to
observe Neelís relaxation. Our goal is to combine the advantages of CMOS technology and the numerous
applications of Flow Cytometry to meet the needs of point-of-care diagnostics.

Current Active Projects:

     Last Updated: Tue 2014-Feb-18 14:51:27

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