BIOGRAPHY

Modular Biomolecular Signal Amplification for Colorimetric Point-of-Care Diagnostics [BPN543]
Predictive and preventive diagnostics promise to dramatically improve targeted patient
healthcare while vastly reducing systemic costs. However, patients in remote and resource-poor
settings have significantly reduced access to valuable diagnostics. We are integrating nucleic acid
based molecular recognition elements into microfluidic devices to achieve quantitative measures of a
range of biomarkers without the need for external equipment. We have further designed an opto-
biochemical signal amplification component for downstream readout. We aim to reduce assay cost, time-
to-answer, and sensitivity to environmental limitations, leading to effective diagnostics for
resource-poor settings.