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Brian Pepin, M.S. 2014

Advisor: Prof. Maharbiz
Research Interests: Metal-on-polymer MEMS, biological sensing
Job Interests: Industry R&D, Entrepreneurial Ventures

BIOGRAPHY

Transparent Microelectrode Arrays for Hybrid Experiments in Neuroscience [BPN726]
Optogenetics techniques that have been developed over the previous decade allow cell-type
specific optical stimulation of neurons in-vivo. However, it remains a challenge to perform
simultaneous electrical recording while providing optical stimulation due to photoelectric artifact
generated at the microelectrode recording sites. This project aims to address this challenge by
developing bio- compatible microelectrode arrays with optically transparent recording sites.
Current devices are optimized for performing electrocorticography (ECoG) experiments and use
Indium-Tin Oxide (ITO, a transparent conductive oxide) as the electrode material. Preliminary
characterization of the arrays indicate electrode impedances as low as 100kOhm and show no
photoelectric artifact. These micro- ECoG (uECoG) arrays are currently being validated in a variety
of novel hybrid neuroscience experiments combining optical stimulation with electrical recording,
both at Berkeley and with collaborators at other universities.


 

     Last Updated: Fri 2014-Feb-28 23:54:52

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