Research Interests: CMOS Bio-Sensors, Point of care diagnostic devices.Job Interests: Internship in summer 2014 at an Industry R&D focused on point of care diagnostics
Pramod obtained his B.Tech degree in Electronics and Comm. Engg. from National Institute of Technology, Surathkal in 2009 and M.E degree in Microelectronic Systems from Indian Institute of Science, Bangalore in 2011. He worked as a Project Associate at the Centre for NanoScience and Engineering, Bangalore from 2011-2012. Currently he is a graduate student at U C Berkeley working with Prof. Bernhard Boser and Prof. Ali Niknejad.
Magnetic Particle Flow Cytometer [BPN649]
Flow Cytometry is a powerful technique used in health and disease diagnostics. This
technique is used to analyze and sort individual cells of a biological sample. Some of the
applications include, HIV and cancer detection, water quality monitoring, food safety among many
others. Commercial equipments use laser source and an optical detector to study cells labeled
with fluorescent molecules. Such an approach is expensive, bulky and suffers from optical
background noise. We propose to replace the fluorescent markers with magnetic nano-particles
(MNPs) to be detected by CMOS chips. Apart from eliminating the need for sample preparation, this
approach has the advantage of being low cost, portable and disposable. Neelís relaxation of MNPs
leads to a frequency dependent complex susceptibility behaviour. The relaxation time constant
depends on the nano-particle size and material. We use this phenomenon to distinguish different
cells. Currently, we are in the process of characterizing different MNPs to observe Neelís
relaxation. Our goal is to combine the advantages of CMOS technology and the numerous
applications of Flow Cytometry to meet the needs of point-of-care diagnostics.