BERKELEY SENSOR & ACTUATOR CENTER
UC BERKELEY UC DAVIS
User: Guest |  Site Map |  My BSAC Profile
HOME  PROJECTS  THRUSTS  PUBLICATIONS  ABOUT BSAC  DIRECTORY  ALUMNI  FOR BSAC RESEARCHERS  EVENTS CALENDAR  SECURE LOGIN
Visiting Industrial Fellows
     
 
Tom Zajdel, Ph.D. 2018

Electrical Engineering
Advisor: Prof. Maharbiz

Home Page
Research Interests: Bioelectronics. Electrochemical biosensors.
Job Interests: Post-doc.

BIOGRAPHY
Tom J. Zajdel is a PhD Candidate in Electrical Engineering at UC Berkeley, where he designs microsystems that interface with bacterial cells for biosensing. During graduate school, he co-developed "EE40LX: Electronic Interfaces" with Professor Michel Maharbiz, a massive open online course that teaches basic circuit principles, reaching over 80 thousand students worldwide. He is a recipient of the Berkeley Chancellor's Fellowship and the NSF Graduate Research Fellowship. He completed his BS in Electrical and Computer Engineering from The Ohio State University in 2012.

Tethered Bacteria-Based Biosensing [BPN853]
Though the chemotaxis sensing system of emph{Escherichia coli} is known to approach fundamental physical limits for biosensing, few attempts have been made to co-opt the system as the front end for a biohybrid sensor. We propose a biohybrid sensor that monitors chemotactic bacterial flagellar motor (BFM) rotation speed and direction to infer analyte concentration for a low-power, fast, and sensitive response. We present the design and fabrication of a four point impedimetric array that uses current injection electrodes to circumvent electrode polarization screening, enabling solution resistance monitoring within a four-micron by four-micron region. We also demonstrate the first lithographically patterned silica shaft encoders for the BFM, which utilize localized biotin-avidin chemistry to selectively bind to the BFM and encode rotation. When these two components are integrated by bringing the rotating shaft encoders in proximity to the microelectrode array, they will enable an electrochemical method for observing the BFM. Such an impedance-based biohybrid sensor obviates the need for a microscope and in principle may be multiplexed and scaled to large arrays of BFMs, enabling the development of deployable low-power and fast sensing systems that directly observe the BFM to infer analyte concentration.


Current Active Projects:
BPN718
BPN853
 

     Last Updated: Mon 2018-Feb-19 10:37:58

back to Researchers



 

  • Copyright Notification: All papers downloaded from this site are © University of California or the publisher, all rights reserved. Contact the BSAC Webmaster for permission related to copyrighted materials.
  • Links on these pages to commercial sites do not represent endorsements by UC or its affiliates.
  • Privacy Policy
  • Contact Us

   webmaster@bsac.eecs.berkeley.edu
  User logged in as: Guest
  User Idle since: April 19, 2018, 6:38 am