Fall 2010 IAB
September 15 to 17

Justin Valley

Optoelectronic Tweezers for Quantitative Assessment & Sorting Based On Embryo Morphology and Health

We demonstrate a novel technique using Optoelectronic Tweezers (OET) to quantitatively assess the morphological state and health of B6D2F1 mouse embryos. One major factor involved in successful in-vitro fertilization (IVF) is the selection of healthy embryos for implantation. A major indicator of a healthy embryo is its ability to develop quickly relative to its peers. Currently, embryos are selected by an experienced technician who uses solely qualitative observations. A method to quantitatively discern embryos which reach certain developmental stages faster than others could greatly improve the success rate of IVF.