| Project ID |
BPN343 |
| Website |
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| Start Date |
Mon 2006-Feb-06 13:35:17 |
| Last Updated |
Tue 2008-Aug-12 16:56:31 |
| Abstract |
The goal of this project is to develop a robust, reusable, and automated micro-fluidic platform for the manipulation and use of integral membrane proteins and membrane associated proteins. In particular, the goal will be to use an artificially assembled phospholipid bi-layer membrane as an armature for engineered integral membrane proteins, such as alpha-hemolysin (a virulence factor responsible for the lysis of red blood cells). This functionalized membrane will be tested as an active “filtration” element in a sample preparation system, as a stand alone sensing platform with integrated electronics, and as a tool for examining cellular processes at the occurring at or near the membrane. |
| Status |
Continuing |
| Funding Source |
Federal |
| IAB Research Area |
Microfluidics |
| Researcher(s) |
Thomas H. Cauley III |
| Advisor(s) |
Albert P. Pisano |
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