| Project ID |
BPN395 |
| Website |
|
| Start Date |
Tue 2007-Jul-24 20:09:09 |
| Last Updated |
Mon 2009-Aug-10 22:49:27 |
| Abstract |
This project presents a new single-cell analysis tool, flow-lysometry, for the cytosolic ATP measurement. Single-cell analysis
by flowcytometry has revolutionized the measurement of complex cell populations. Only limited probes are available for the
measurement of cytosolic components in single cells. While cellular components such as ATP can be measured sensitively in a
suspension of cells with permeabilized plasma membranes, the determination of the distribution of such compounds in individual
cells in a heterogeneous population is not available. We propose the development a novel technique, flow-lysometry, by a multi-
disciplinary approach, combining cell biology and nanotechnology developed by micromechanical engineering, to measure cytosolic
components of single cells. |
| Status |
Continuing |
| Funding Source |
Other |
| IAB Research Area |
BioMEMS |
| Researcher(s) |
Won Chul Lee |
| Advisor(s) |
Albert P. Pisano |
|
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