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BPN438: uPAUM: A Micropost Array for Unidirectional Cell Migration

Project ID BPN438
Website
Start Date Thu 2008-Jan-24 13:36:24
Last Updated Mon 2009-Aug-24 17:42:10
Abstract Controlling cell migration is integral to a variety of applications in both tissue engineering and medical device implantation. Mechanical properties of the substrate influence cell behavior and it has been previously demonstrated that certain cells migrate in the direction of increasing substrate rigidity. Prior research with micropatterned substrates has successfully limited cell motility to biaxial movement. Our goal is to develop microtopographic gradients which enable unidirectional control of cellular migration.
Status Continuing
Funding Source Other
IAB Research Area BioMEMS
Researcher(s) Ryan D. Sochol, Adrienne T. Higa
Advisor(s) Liwei Lin, Song Li
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