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BioMEMS
     
 

BPN543: Modular Biomolecular Signal Amplification for Colorimetric Point-of-Care Diagnostics

Project ID BPN543
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Start Date Fri 2010-Jan-29 00:09:31
Last Updated Wed 2013-Aug-14 23:50:20
Abstract Predictive and preventive diagnostics promise to dramatically improve targeted patient healthcare while vastly reducing systemic costs. However, patients in remote and resource-poor settings have significantly reduced access to valuable diagnostics. We are integrating nucleic acid based molecular recognition elements into microfluidic devices to achieve quantitative measures of a range of biomarkers without the need for external equipment. We have further designed an opto- biochemical signal amplification component for downstream readout. We aim to reduce assay cost, time- to-answer, and sensitivity to environmental limitations, leading to effective diagnostics for resource-poor settings.
Status Continuing
Funding Source Federal
IAB Research Area Microfluidics
Researcher(s) Richard H. Henrikson, John R. Waldeisen
Advisor(s) Luke P. Lee
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