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BPN649: Magnetic Particle Flow Cytometer

Project ID BPN649
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Start Date Thu 2011-Aug-18 11:17:59
Last Updated Tue 2014-Aug-12 13:36:42
Abstract The goal of this project is to come up with a low cost, portable and disposable alternative to a flow cytometer, a powerful tool used in health and disease diagnostics. Commercial flow cytometers use fluorescent labels and optical detectors. These equipments are expensive, bulky and suffer from optical background noise. We have replaced the fluorescent markers with magnetic labels and detected them with a CMOS chip. Further, we have developed a unique hot embossing technique for integration of CMOS chips with microfluidics. This technique can potentially benefit large scale production of chip scale cytometers. Our current focus is to design the system for detection of circulating tumor cells for metastatic breast or prostate cancer.
Status Continuing
Funding Source BSAC Member Fees
IAB Research Area BioMEMS
Researcher(s) Pramod Murali
Advisor(s) Bernhard E. Boser
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