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BPN726: Transparent Microelectrode Arrays for Hybrid Experiments in Neuroscience

Project ID BPN726
Website
Start Date Thu 2013-Aug-15 12:15:39
Last Updated Mon 2014-Feb-03 16:15:54
Abstract Optogenetics techniques that have been developed over the previous decade allow cell-type specific optical stimulation of neurons in-vivo. However, it remains a challenge to perform simultaneous electrical recording while providing optical stimulation due to photoelectric artifact generated at the microelectrode recording sites. This project aims to address this challenge by developing bio- compatible microelectrode arrays with optically transparent recording sites. Current devices are optimized for performing electrocorticography (ECoG) experiments and use Indium-Tin Oxide (ITO, a transparent conductive oxide) as the electrode material. Preliminary characterization of the arrays indicate electrode impedances as low as 100kOhm and show no photoelectric artifact. These micro- ECoG (uECoG) arrays are currently being validated in a variety of novel hybrid neuroscience experiments combining optical stimulation with electrical recording, both at Berkeley and with collaborators at other universities.
Status Continuing
Funding Source BSAC Member Fees
IAB Research Area Physical Sensors & Devices
Researcher(s) Brian Pepin
Advisor(s) Michel M. Maharbiz, Timothy J. Blanche
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