Research Interests: Medical devices
Monica Lin is PhD student in the UC Berkeley - UCSF Graduate Program in Bioengineering, with a research focus on medical devices. She is interested in developing sensors to address unmet clinical needs, and currently works in Dr. Michel Maharbiz's lab developing an electronic bandage to detect pressure ulcers and another device to monitor fracture healing.
Impedance Spectroscopy to Monitor Fracture Healing [BPN780]
An estimated 15 million fracture injuries occur each year in the United States. Of these,
10% of fractures result in delayed or non-union, with this number rising to 46% when they occur
in conjunction with vascular injury. Current methods of monitoring include taking X-rays and
making clinical observations. However, radiographic techniques lag and physician examination of
injury is fraught with subjectivity. No standardized methods exist to assess the extent of
healing that has taken place in a fracture, revealing the need for a diagnostic device that can
reliably detect non-union in its early pathologic phases. Electrical impedance spectroscopy has
been used to characterize different tissues, and we hypothesize that this technique can be applied
to fractures to distinguish between the various types of tissue present in the clearly defined
stages of healing. We are developing an objective measurement tool that utilizes impedance
spectroscopy to monitor fracture healing, with the goal of providing physicians with more
information that can resolve the initial stages of fracture healing. This would enable early
intervention to prevent problem fractures from progressing to non-union.