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Projects by Director

Prof. Luke P. Lee
(510) 642-5855
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Titles of Current Projects:
BPN884: Anisotropic Proton Transport in Artificially Aligned Collagen Fiber
BPN829: Integrated Multiplexed Optical Microfluidic System (iMOMs) for Dengue Diagnosis
BPN809: Photonic Cavity Bioreactor for High-throughput Screening of Microalgae

Recently Ended Projects:
BPN836: Nanocrescent Antenna for Nanofocusing of Excitation Radiation and Concentrate Upconversion Emission
BPN824: Investigation of Dengue Infection’s Neurological Complications via a Comprehensive In Vitro Brain Model
BPN804: A Rapid, Integrated Molecular Diagnostic for Gram-Negative Pathogen Detection and Identification Based on Antibody-Based Capture and Photonic PCR
BPN730: Microfluidic Blood Plasma Separation for Point-of-Care Diagnostics
BPN831: Sample-to-Answer Multiplex Molecular Diagnostics for Subtyping Pathogenic Bacteria
BPN807: Integrated Molecular Diagnostic System for Alzheimer’s Disease
BPN811: High-Throughput Integrated Chiral Analysis Platform (hiCAP) for Active Drug Discovery
BPN830: High-throughput Integrated Chiral Analysis Platform (hiCAP) for Active Drug Discovery
BPN794: Bubble-Free Microfluidic PCR
BPN806: Very Large Scale Single Cell Microprocessor for Rapid Gene Analyzer: A Game-Changer for Single Cell Biology and Medicine
BPN805: Rapid Detection of Drug-resistant Gram-Negative Bacteria on Chip
BPN775: Integrated Microfluidic Circuitry via Optofluidic Lithography
BPN778: Single-cell MicroRNA Quantification for Gene Regulation Heterogeneity Study
BPN773: Human Induced Pluripotent Stem Cell-derived Hepatocytes (hiPSC-HPs)-based Organs on Chip
BPN791: Integrated Photobioreactor with Optical Excitation Membranes (iPOEMs) for Efficient Photosynthetic Light Harvesting
BPN679: Portable Microfluidic Pumping System for Point-Of-Care Diagnostics
BPN727: On-Chip Single Molecule miRNA Detection for Cancer Diagnosis
BPN723: Organ-on-a-Chip for Personalized Medicine Development
BPN473: Next-Generation Microfluidic Components, Circuits and Systems
BPN725: One-Step Electrokinetic Nucleic Acid Preconcentrator for PCR-Based Point-of-Care Diagnosis
BPN653: Biologically-Inspired, Self-Activated Building Envelope Regulation System (SABERS)
BPN728: Paper-Based Integrated Diagnostic Chip for Nucleic Acid Detection of HIV from Blood
BPN611: Integrated Amplification and Readout for Multiplexed Biomarker Detection in a Rapid, Simple and Inexpensive Microfluidic System
BPN543: Modular Biomolecular Signal Amplification for Colorimetric Point-of-Care Diagnostics
BPN668: Microfluidic Chemo-Sensitivity Assay Platform (µCAP) for Personalized Breast Cancer Therapy and Research
BPN627: Stencil Patterning Method Improves Uniformity of Human Pluripotent Stem Cell Colonies
BPN512: Electrophysiological Cell Sorting
BPN692: DNA Sequencing by Graphene Nanopores with Integrated Plasmonic Nanoantennas
BPN680: Solar Optics-based Active Panels (SOAP) for Photocatalytic Greywater Treatment: Design and Kinetics
BPN669: Universal Blood Sample Preparation
BPN691: Nanoplasmonic Imaging of Specific Biochemical Data in Living Cells
BPN674: Integrated Microfluidic Array Plate (iMAP) for Cellular and Molecular Analysis
BPN673: Gold Virus Nanoparticle for Molecular Imaging
BPN650: Nanopores Generated by Photothermal Plasmic Antennas for Patterable In Situ Transfection in Tissue-scale
BPN598: Toward Silk-based Biomedical Devices
BPN633: Numerical Simulation of Degas-driven Flow in Microfluidic Devices
BPN632: Advanced Lateral Flow Assay (ALFA) to Monitor Tuberculosis Patient Response
BPN637: Novel Molecular Diagnostics Based on RNAi for HIV Detection
BPN580: Nanovolcano Array For Biomolecular Analysis
BPN600: Nanogap Junction Control of Gold Optical Antennas via Electroless Deposition
BPN547: Eagle-Beak Nanoantenna as Dual Electric Field and Thermal Gradient Generator for Single Molecule SERS
BPN589: Microfluidic High-Throughput Single-Cell Analysis
BPN529: Sepsis Diagnostics Using iMDs
BPN619: Digital Microfluidics Based Label-free Technique for Selective and Sensitive Detection and Identification of Biological Molecules; Plasmonic Droplet
BPN513: Direct Synthesis of High Density Mono-Dispersed Gold Nano Particle and Biomedical Applications
BPN615: Integrated Microfluidic CMOS (imCMOS) for Quantitative Cell Biology
BPN569: Beta-Amyloid-Induced Membrane Perturbation and Cation Dyshomeostasis in Neurons and Relation to Alzheimer's Disease
BPN617: Optofluidic Controls and Multi-Photon Real-Time Imaging of Cell Reprogramming
BPN618: Reprogramming Cells on a Chip
BPN568: A Real-time PCR Antibiogram for Drug-resistant Septicemia
BPN587: Nuclear Reprogramming by Microslits Confined Cytoplasm Fusion
BPN536: Absorptive h-PDMS Plasmonic Nanopillars: A Replicable Substrate for Generating High SERS Signals by Chemical Concentration
BPN585: High Efficiency Transfection of Cell Reprogramming Factors Using µF-TFT Electroporation Array
BPN508: Carbon Nanotubes as Scaffolding for Surface-enhanced Raman Spectroscopy
BPN523: Bio-Inspired Manipulation of Nanoplasmonic Architectures via Active Polymers
BPN511: Selective Delivery of anti-Akt siRNA via Frequency-Tuned Nanoparticles for the Study of Angiogenesis
BPN319: Quantitative Study on Cancer Research: Aptasensor for Cancer Diagnostics
BPN548: Selective Amplification of Raman Scatterings using Optical Nano-Antennas
BPN328: Remote Nanoplasmonic Switch for Localized Gene Silencing
BPN514: The Disassembly of a Core-Satellite Nanoassembled Substrate for Colorimetric Biomolecular Detection
BPN345: Biomimetic Microfluidic Silk Gland
BPN379: PRET-based Molecular Imaging on Integrated Optofluidic Nanoplasmonic Platform
BPN380: Plasmon Resonance Energy Transfer (PRET)-based Nanospectroscopic Metal Ion Detection
BPN516: Sensing Biomolecules through Crescent-Shaped Nanoholes
BPN515: Nanoplasmonic Antenna on Hexagonal Mirror Array for SERS
BPN447: BioMolecular Plasmonics of 'Nanocrown'
BPN471: Nanogap Plasmonic Mirror Structure for Surface Enhanced Spectroscopy
BPN509: Plasmonic Transfection With Single Cell Resolution
BPN489: Aluminum Plasmonic Nanoantennas for Label-free Protein Detection
BPN492: Integrated Microfactory for Nanostructure Synthesis
BPN429: Plasmonic Nanocrescent Array for Ultrasensitive Biomoleculer Detection
BPN476: Integrated Plasmonic Optical Trapping (iPOT)
BPN417: Spatially Targeted Microfluidic Stimulation for Quantitative Gap Junction Analysis
BPN430: In-vivo Cellular Mapping of Biological Activity by Quantized Plasmon Quenching Dips Nanospectroscopy
BPN355: Microfluidic Cell Analysis Platform: On Chip Cell Culture and Electrochemical Lysis
BPN340: Single cell differential impedance spectroscopy analysis using high density hydrodynamic cell trapping arrays
BPN449: Plasmon Engineering the Nanocrescent
BPN398: Single Cell Electroporation Array with OET/PDMS Integration
BPN344: Microfluidic Platform for Quantitative Microcirculation Studies in Sickle Cell Disease
BPN384: Single-cell Analysis via Raman Spectroscopy
BPN312: High Precision Kinematic Assembly of Soft-State Biofluidic ASICs
BPN409: Long-term Cytotoxic Drug Assay via Single-Cell Microfluidic Array
BPN412: Signal Amplifications of SERS by Microfluidic CD-based Preconcentration Methods
BPN360: Biomimetic Microfluidic Assembly of Spheroids and Dynamic Perfusion for Anti-Cancer Drug Discovery
BPN378: High-Density Spheroid Arrays for 3-D Liver Cell Culture and Secretion Analysis
BPN381: SERS Signal Amplification by Optofluidic Photothermal Sample Preconcentration
LPL31: Soft-state Biomicrofluidic Pulse Generator for Single Cell Analysis
BPN377: Quantitative Cell Adhesion Study for High Throughput Cancer Cells Screening using a Centrifugal Microfluidic CD Platform
BPN313: Biologic Application Specific Integrated Circuits (BASICs) for the Selective Amplification of Cancer Cells and Harvesting Cancer Biomarkers
BPN322: Microfluidic Multiplexed Cytokine Secretion Assay
LPL37: Nanoplasmonic Genomics/Proteomics Chip
BPN302: Unconventional nanoplasmonic structures for photothermal applications
LPL23: Nanogap Junction Capacitors For Biomolecular Detection
LPL42: Multifunctional Nano-Crescent Probes for Molecular Imaging of Intracellular Signaling Pathway
LPL5: Microfluidic Cellular Manipulation - Single cell trapping arrays for quantitiative cell biology
BPN314: Biomimetic Infrared sensor based on the nanogap junction array
LPL38: Electrophysiology Using a High-Density Microfluidic Array
LPL39: Integrated Microfluidic SERS Devices
LPL35: Microfluidic Cell Culture Array
LPL41: Raised Lateral Patch Clamp Array
LPL32: Disposable Multi Patch Clamps Using Planar Fludic Channels
LPL34: Single-Cell Electroporation Microchip
LPL40: Digitized Microfluidic Device for Single Cell Analysis
LPL36: Behavior of water and ice in nanocavities
LPL33: Time Division Multiplexed Microfluidic Lateral Patch Clamp Array
LPL21: Biomimetic Microfabricated Compound Eyes
LPL28: Microfluidic-Based Two-Dimensional Protein Chip
LPL18: Nanopillar Substrate for Surface-Enhanced Raman Spectroscopy
LPL20: A new pressure tranduction mechanism using elastomer micromolding
LPL11: Integrated Polymer Actuators in Microfluidic Systems
LPL27: Biomimetic Imager as Omnidirectional Sensor (BIOS)
LPL25: Tunable Microdoublet Lens Array
LPL29: Nanoprobes for Monitoring Sub-cellular Response to Localized Surface Interactions
LPL22: Electronic Properties of DNA for Bioelectronics
LPL13: Vertically-Integrated Micro Confocal Imaging Array (VIµ-CIA)
DL12: Fluid Dynamics in Nanoscale Environments
LPL30: 3D Alignment of Collagen Fibrils in Microchannels
LPL10: Disposable Integrated Optical MEMS and Microfluidic Channels for High Resolution Biochip Array
LPL26: Floating planar nanogap capacitor for biosensor application


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