| Project ID |
BPN733 |
| Website |
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| Start Date |
Thu 2014-Jan-23 09:51:44 |
| Last Updated |
Tue 2015-Feb-03 12:19:08 |
| Abstract |
In contrast to bulk analysis, analyzing biological samples on a single-cell level is
a powerful tool in deriving a more complete, quantitative understanding of cellular
behavior. The optoelectronic tweezers (OET) platform utilizes light-generated
dielectrophoretic force to manipulate micro-scale objects reconfigurably on the device
surface. Consequently, OET is able to select for individual cells and manipulate them
into a specific configuration where these cells are cultured and studied for an
extended period of time. Compared to trap-based single-cell techniques, the OET platform
provides advantages such as specific selection of an individual cell and subsequent
culturing over a larger-scale area at a particular address on the surface of the device.
We are looking to apply the OET platform for long- term culture of single cells and gain
useful insights into topics such as rate of proliferation, differentiation, and changes
in morphology and protein expression. |
| Status |
New |
| Funding Source |
BSAC Member Fees |
| IAB Research Area |
Microfluidics |
| Researcher(s) |
Shao Ning Pei, Tiffany Dai |
| Advisor(s) |
Ming C. Wu, Song Li |
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